Making Human Organs Talk To Decode Drugs

Invexo turns discarded human organs into living testbeds for drug development

Our Solution

Invexo keeps discarded human organs outside the body under controlled, standardised conditions turning them into a programmable testbed for drug and device developers. In a single study, customers get pharmacokinetic parameters, metabolite profiles, toxicity biomarkers and imaging readouts generated on real human tissue, not animal proxies.

De-risk go/no-go decisions

Identify organ-specific liabilities in human tissue before clinical investment, increasing confidence & clinical success rates at a fraction of the cost of a failed trial.

Faster route to market

Compress preclinical cycles by 6 months to 2 years*, front-load human-relevant evidence and reduce Phase I bottlenecks by 20-30%*. *data still to be proven estimated numbers

Ethical readouts in disease-relevant models

Replace inaccurate animal studies with safety and efficacy readouts in healthy and diseased human organ statesthe precise biological context that matters.

Stronger regulatory packages

Regulatory-grade human data (pre-IND, pre-submission) aligned with the emerging FDA/EMA Novel Approach Methodology framework, generated under GLP-aligned protocols.

A second value layer builds underneath the science: every study contributes to a structured, labelled human organ dataset, the kind of human-derived training data AI drug discovery companies increasingly need and cannot source at scale.

Our direct customers would be:

Pharma & Biotech MLEs

Medtech SMEs and MLEs 

Contract Research Organisations (CROs) 

AI drug discovery companies 

Multi-Modal Data Outputs

Patient Metadata
Donor demographics, clinical history, comorbidities & consent records linked to every study
Layer 1
Organ Viability & Functionality
Real-time perfusion metrics, bile flow, vascular resistance & organ-specific functional biomarkers
Layer 2
Drug Metabolism & Molecular Profiling (PK/PD)
Pharmacokinetic parameters, metabolite identification, CYP450 activity & toxicity biomarkers
Layer 3
Multi-Modal Imaging
Ultrasound, fluorescence, photoacoustic & laparoscopic imaging captured throughout the study window
Layer 4
Histology & Tissue Biology
H&E, IHC & spatial transcriptomics on end-point tissue samples — ground-truth pathological readouts
Layer 5

Who are we?

Invexo is a project emerging from University College London (UCL). Six years of research have taken the platform to a working prototype.

Loïc Lerville-Rouyer

Co-Founder & Project Lead

More About Loïc

Biomedical engineer with formative research experience in organ perfusion at UCL and regulated medtech R&D at Johnson & Johnson’s Center for Device Innovation. Previously led Asclepios, the first and only international student-led analog space mission, securing institutional collaborations with NASA and ESA. Leads Invexo’s strategy, commercial engagement and stakeholder relationships.

Loic linkedin 

Dr Morenike Magbagbeola

Co-Founder &  Technology Lead

More About Morenike

PhD in Adaptive Robotics from UCL, five years of postdoctoral research developing organ perfusion devices. Subsequently Lead Robotics Engineer at BP and Autonomous Systems Engineer at Wayve, one of Europe’s leading AI robotics companies. Leads the design, engineering and automation of Invexo’s perfusion platform.

Morenike Linkedin  

Dr Zainab Rai

Co-Founder & Clinical Lead

More About Zainab

MD and Clinical Research Fellow at UCL specialising in hepato-pancreato-biliary (HPB) surgery, the precise clinical domain in which drug metabolism and organ-level toxicity are most relevant. Five years of organ perfusion research experience and Principal Investigator on translational studies with awards from the Royal College of Surgeons, NIHR and Pancreatic Cancer UK. Leads clinical research, human tissue ethics and regulatory engagement.

Zainab Linkedin  

Prof. Brian Davidson

Scientific & Advisory Board

More About Brian

Consultant HPB and Liver Transplant Surgeon at the Royal Free Hospital and Head of Surgical Innovation at UCL. Author of 600+ peer-reviewed publications and Principal Investigator on 6 clinical trials in oncological treatments. Brings direct clinical credibility, deep transplant-network access and translational research leadership at one of the UK’s leading HPB centres.

Brian LinkedIn 

Prof. Dan Stoyanov

Scientific & Advisory Board

More About Dan

Co-Director of the Hawkes Institute at UCL and Royal Academy of Engineering Chair in Emerging Technologies. Pioneer in surgical robotics and AI with 70+ patents. Co-founder of multiple deep-tech companies including a £200M exit, Chief Scientist at Medtronic. Brings IP strategy, deep-tech commercialisation experience and industry credibility.

Dan LinkedIn 

Dr Agostino Stilli

Scientific & Advisory Board

More About Agostino

Associate Professor in Medical Robotics at UCL and Rosetrees Enterprise Fellow. Bridges robotics research and venture creation, with direct experience translating academic robotics IP into commercial ventures. Reinforces the platform’s robotics engineering and early-stage venture capability.

Agostino LinkedIn  

Get in touch

We would love your feedback on our technology.

Our technology is ideally suited for Pharma & Biotech MLEs, CROs, Medtech and AI Drug Discovery.

Speak To Our Team!